The Impact of Sitting All Day – Part 3
In part 1, I looked at the impact of sitting on your muscles, and in part 2 I started to explore the impact on the rest of your body. In this post I continue to explore the impact of sitting on your circulatory system including your heart.
Heart Disease
When sitting for prolonged periods of time, muscles burn less fat and blood flows more sluggishly, allowing fatty acids to more easily clog the heart. In 2012 Ford & Caspersen in their research paper, Sedentary behaviour and cardiovascular disease: a review of prospective studies (International Journal of Epidemiology, Vol 41, No 5 pages 1338 – 1353) showed that the people with the most sedentary time are more than twice as likely to have cardiovascular disease than those with the least.
In 2012 Zedric and Hamilton found that just a few hours sitting suppresses a gene that helps keep your cardiovascular system healthy by controlling inflammation and blood clotting.
T W Zedric & M T Hamilton, 2012 Identification of hemostatic genes expressed in human and rat leg muscles and a novel gene (LPP1/PAP2a) suppressed during prolonged physical inactivity (sitting), Lipids in Health and Disease, Vol 11 see http://www.biomedcentral.com/content/pdf/1476-511X-11-137.pdf
Cholesterol
Sitting also means that your large postural support muscles are inactive. When active these muscles produce a quite of beneficial molecules. One molecule skeletal muscles produce is an enzyme called lipoprotein lipase – which you can think of as a vacuum cleaner for fats in the blood stream. A study in rats showed that after 24 hours forced inactivity, their lipoprotein lipase acitivity was reduced by 90 – 95%, which led to a 75% drip in the ability of their muscles to remove fats from their bloodstream as will as a significant decrease in “good” (HDL) cholesterol.
L Bay & Mark Hamilton, 2003, Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity, Journal of Physiology, Vol 551, No 2 pages 673 – 682.See http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2003.045591/full
Related Posts

The Impact of Sitting All Day – Part 7
There is a wide range of American start up companies, creating technology solutions to combat the new "sitting disease". In previous posts I have discussed in the impact of sitting all day
- the impact on muscles (in part 1)
- the general impact on the body (in part 2)
- the impact on your heart and the increase risk of cardiovascular disease (in part 3)
- the increased risk of certain cancers (in part 4)
- 1. Apple Watch
- 2. Jawbone UP
- 3. Nike+ Fuelband
- 4. Fitbit One

Myofascia – part 1
What is Myofasci? Fascia is the main connective tissue of the body. Fascia surrounds every cell, muscle, bone, nerve, blood Bessel in the body, creating a three-dimensional web. This is one continuous network from head to toe. Myofascia is the fascia that surrounds all the muscle. Why it is important? In its normal state fascia is fluid and pliable, allowing full, pain-free movement. However, fascia is vulnerable to trauma from
- Accident
- Infection
- Injury
- Surgery
- Repetitive Movement
- Habitual Poor Posture
- Poor biomechanics
- Altered structural alignment
- Compromised blood supply
- Pain
- Reduce flexibility and stability

Scientific Evidence for massage reducing muscle pain
I would say the number one reason for booking with Vitality Therapy is muscle pain in either
- Shoulders
- Neck
- Lower Back
- Knees
- Elbows
- Headaches
- Cherkin D, Sherman K, Deyo R, Shekelle P. A review of the evidence for the effectiveness, safety, and cost of acupuncture, massage therapy, and spinal manipulation for back pain. Ann Intern Med 2003; 138(11): 898-906.
- Chou R, Huffman L. Nonpharmacologic therapies for acute and chronic low back pain: a review of the evidence for an American Pain Society/American College of Physicians clinical practice guideline. Ann Intern Med 2007; 147(7): 492-504.
- Dryden T, Baskwill A, Preyde M. Massage therapy for the orthopaedic patient: a review. Orthop Nurs 2004; 23(5): 327-34.
- Furlan A, Brosseau L, Imamura M, Irvin E. Massage for low-back pain: a systematic review within the framework of the Cochrane Collaboration Back Review Group. Spine 2002; 27(17): 1896-910.
- Imamura M, Furlan A, Dryden T, Irvin E. Evidence-informed management of chronic low back pain with massage. Spine J 2008; 8(1): 121-33.
- Tsao J. Effectiveness of Massage Therapy for Chronic, Non-malignant Pain: A Review. Evid Based Complement Alternat Med 2007; 4(2): 165-79.
- van Tulder M, Furlan A, Gagnier J. Complementary and alternative therapies for lower back pain. Best Pract Res Clin Rheumatol 2005; 19(4): 639-54

