The Impact of Sitting All Day – Part 3

In part 1, I looked at the impact of sitting on your muscles,  and in part 2 I started to explore the impact on the rest of your body.  In this post I continue to explore the impact of sitting on your circulatory system including your heart.

Heart Disease

When sitting for prolonged periods of time, muscles burn less fat and blood flows more sluggishly, allowing fatty acids to more easily clog the heart.  In 2012 Ford & Caspersen in their research paper, Sedentary behaviour and cardiovascular disease: a review of prospective studies (International Journal of Epidemiology, Vol 41, No 5 pages 1338 – 1353) showed that the people with the most sedentary time are more than twice as likely to have cardiovascular disease than those with the least.

In 2012 Zedric and Hamilton found that just a few hours sitting suppresses a gene that helps keep your cardiovascular system healthy by controlling inflammation and blood clotting.

T W Zedric & M T Hamilton, 2012 Identification of hemostatic genes expressed in human and rat leg muscles and a novel gene (LPP1/PAP2a) suppressed during prolonged physical inactivity (sitting), Lipids in Health and Disease, Vol 11 see http://www.biomedcentral.com/content/pdf/1476-511X-11-137.pdf

Cholesterol

Sitting also means that your large postural support muscles are inactive.  When active these muscles produce a quite of beneficial molecules.  One molecule skeletal muscles produce is an enzyme called lipoprotein lipase – which you can think of as a vacuum cleaner for fats in the blood stream.  A study in rats showed that after 24 hours forced inactivity, their lipoprotein lipase acitivity was reduced by 90 – 95%, which led to a 75% drip in the ability of their muscles to remove fats from their bloodstream as will as a significant decrease in “good” (HDL) cholesterol.

L Bay & Mark Hamilton, 2003, Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity, Journal of Physiology, Vol 551, No 2 pages 673 – 682.See http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2003.045591/full

Related Posts

  • The Impact of Sitting All Day – Part 7

    There is a wide range of American start up companies, creating technology solutions to combat the new "sitting disease".  In previous posts I have discussed in the impact of sitting all day

    In my post, "Taking a Break", I explored the reasons for taking a break and looked at the latest research on the length of break you need to take and the frequency.  In my last blog post, "Get Moving" I looked at how you can move while working.  In this post I want to review the technology solutions that are out there. Activity Trackers Most of the technology solutions currently available are wearable activity trackers. These products are basically advanced sensors that come embedded inside of bracelets or clips that hook onto your clothing. They measure your daily activity (steps taken and calories burned), sleep, and through an associated app, diet.  Below I list some of the common trackers.
    • 1. Apple Watch
    Everyone knows that Apple is about to launch the Apple Watch which will have a plethora of health and fitness functionalities. However the Apple Watch heavily relies on the iPhone to function and is not really considered a standalone device. But I want to focus on one interesting feature which is that ten minutes before each hour, the Apple Watch taps on their arms as an alert to ecourage you to stay active or just simply stand up. I can see this being essential for people who want to stay active but find they lose track of time when they work.
    • 2. Jawbone UP
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    • 3. Nike+ Fuelband
    What is good about the Nike+ Fuelband activity tracker is that lets you set an activity goal, you can press a button on an LED screen to check your progress, and displays a green light when you have achieved your goal.  However it can be inaccurate if for some reason you happen to move your hands swiftly throughout the day.
    • 4. Fitbit One
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    1. Cherkin D, Sherman K, Deyo R, Shekelle P. A review of the evidence for the effectiveness, safety, and cost of acupuncture, massage therapy, and spinal manipulation for back pain. Ann Intern Med 2003; 138(11): 898-906.
    2. Chou R, Huffman L. Nonpharmacologic therapies for acute and chronic low back pain: a review of the evidence for an American Pain Society/American College of Physicians clinical practice guideline. Ann Intern Med 2007; 147(7): 492-504.
    3. Dryden T, Baskwill A, Preyde M. Massage therapy for the orthopaedic patient: a review. Orthop Nurs 2004; 23(5): 327-34.
    4. Furlan A, Brosseau L, Imamura M, Irvin E. Massage for low-back pain: a systematic review within the framework of the Cochrane Collaboration Back Review Group. Spine 2002; 27(17): 1896-910.
    5. Imamura M, Furlan A, Dryden T, Irvin E. Evidence-informed management of chronic low back pain with massage. Spine J 2008; 8(1): 121-33.
    6. Tsao J. Effectiveness of Massage Therapy for Chronic, Non-malignant Pain: A Review. Evid Based Complement Alternat Med 2007; 4(2): 165-79.
    7. van Tulder M, Furlan A, Gagnier J. Complementary and alternative therapies for lower back pain. Best Pract Res Clin Rheumatol 2005; 19(4): 639-54