The Impact of Sitting All Day – Part 2

In part 1, I looked at the impact of sitting on your muscles, but what happens in the rest of your body?

Leg Disorders

We are all familiar with the risk of deep vein thrombosis (DVT) if we take long flights.  This is because sitting for long periods of time slows blood circulation, which causes fluid to pool in legs.  This creates problems ranging from swollen ankles, varicose beings to dangerous blood clots.

Soft Bones

Osteoporosis is a disease marked by reduced bone strength leading to an increased risk of fractures, or broken bones. Bone strength has two main features: bone mass (amount of bone) and bone quality.  Osteoporosis is often called a “silent disease” because it usually progresses without any symptoms until a fracture occurs or one or more vertebrae (bones in the spine) collapse.   Weight-bearing activities such as walking and running stimulate hip and lower-body bones to grow thicker, denser and stronger.  Medical researchers partially attribute the recent surge in cases of osteoporosis to lack of activity.

Garrett, Brasure et al, 2004, Physical Inactivity Direct Cost To A Health Plan, American Journal of Preventative Medicine; Vol 27 No 4, Pages 304–309 See http://www.ajpmonline.org/article/S0749-3797%2804%2900191-6/abstract?cc=y

Weight Gain

As the body slows down while in a resting and seated positions, the metabolism naturally slows down.  Calories are burned at a far lower rate, when you sit, you burn only about one calorie a minute!.  For some people this can lead to weight gain becoming an issues.  Being overweight is a known risk factor for many common chronic conditions including

  • diabetes
  • gallstones
  • hypertension
  • heart disease
  • stroke

Field, Coakley et al, 2001 Impact of Overweight on the Risk of Developing Common Chronic Diseases During a 10 Year Period, JAMA Internal Medicine; Vol 161 No13, Pages 1581-1586.  See http://archinte.jamanetwork.com/article.aspx?articleid=648604

 

 

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  • The Impact of Sitting All Day – Part 3

    In part 1, I looked at the impact of sitting on your muscles,  and in part 2 I started to explore the impact on the rest of your body.  In this post I continue to explore the impact of sitting on your circulatory system including your heart. Heart Disease When sitting for prolonged periods of time, muscles burn less fat and blood flows more sluggishly, allowing fatty acids to more easily clog the heart.  In 2012 Ford & Caspersen in their research paper, Sedentary behaviour and cardiovascular disease: a review of prospective studies (International Journal of Epidemiology, Vol 41, No 5 pages 1338 - 1353) showed that the people with the most sedentary time are more than twice as likely to have cardiovascular disease than those with the least. In 2012 Zedric and Hamilton found that just a few hours sitting suppresses a gene that helps keep your cardiovascular system healthy by controlling inflammation and blood clotting. T W Zedric & M T Hamilton, 2012 Identification of hemostatic genes expressed in human and rat leg muscles and a novel gene (LPP1/PAP2a) suppressed during prolonged physical inactivity (sitting), Lipids in Health and Disease, Vol 11 see http://www.biomedcentral.com/content/pdf/1476-511X-11-137.pdf Cholesterol Sitting also means that your large postural support muscles are inactive.  When active these muscles produce a quite of beneficial molecules.  One molecule skeletal muscles produce is an enzyme called lipoprotein lipase - which you can think of as a vacuum cleaner for fats in the blood stream.  A study in rats showed that after 24 hours forced inactivity, their lipoprotein lipase acitivity was reduced by 90 - 95%, which led to a 75% drip in the ability of their muscles to remove fats from their bloodstream as will as a significant decrease in "good" (HDL) cholesterol. L Bay & Mark Hamilton, 2003, Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity, Journal of Physiology, Vol 551, No 2 pages 673 - 682.See http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2003.045591/full