Guess what scientists have discovered
So, you go to the gym regularly, follow all the latest exercises trends, but are still not getting the results you wanted. It’s frustrating isn’t it. You want that sculptured body, but it seems elusive. Well helps may be coming. Until now scientists haven’t been fully able to understand how muscle responds to exercise especially in the early stages of an exercises program – when we are tempted to give up because we aren’t yet seeing the results.
Scientists at Liverpool John Moores University (LJMU) and the Australian Catholic University in Melbourne have established a new technique for studying muscle growth in humans. The technique, termed Dynamic Proteome Profiling, provides comprehensive coverage of the early changes that occur within human muscle in response to exercise training. This was the first data on the rate at which new muscle proteins are made when volunteers performed strength training exercises.
Muscle is composed of thousands of different proteins and each protein makes a specific contribution to muscle function, for example, some proteins are responsible for movement while others are required to provide energy. The proteins in muscle have a tough time and often become damaged, but in healthy cells a sophisticated recycling system keeps protein quality high by continually breaking down and remaking each protein. When muscle fibres grow in response to weight training the amount of specific proteins is increased, and therefore muscle becomes larger and stronger.
Because of Dynamic Proteome Profiling, scientists are now able to identify exactly which proteins are most responsive to exercise and whether that response is due to more of the protein being made or less of the protein being degraded/ broken down by the cell’s recycling machinery.
This profiling will allow a finer level of detail of muscle response to exercises which could lead to better training methods, nutritional strategies or medicines that can be used to promote muscle growth, and hopefully less frustration on getting the results from hours spent in the gym!
References
https://www.gmjournal.co.uk/scientists-identify-muscle-proteins-most-responsive-to-exercise-1
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- Yao S, Kwan ML, Ergas IJ. Association of Serum Level of Vitamin D at Diagnosis With Breast Cancer Survival A Case-Cohort Analysis in the Pathways Study. JAMA Oncology. 2016
- YA, N, et al. (2016). Associations Between Serum Vitamin D and Adverse Pathology in Men Undergoing Radical Prostatectomy. Journal of Clinical Oncology, 34: 1345-1349
- Sharon L. McDonnell, Carole Baggerly, Christine B. French, Leo L. Baggerly, Cedric F. Garland, Edward D. Gorham, Joan M. Lappe, Robert P. Heaney .Serum 25-Hydroxyvitamin D Concentrations ≥40 ng/ml Are Associated with >65% Lower Cancer Risk: Pooled Analysis of Randomized Trial and Prospective Cohort Study. PLOS ONE, 2016; 11 (4)

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Reference
Roffe C1, Sills S, Crome P, Jones P (2002), Randomised, cross-over, placebo controlled trial of magnesium citrate in the treatment of chronic persistent leg cramps. Med Sci Monit. 2002 May;8(5): p326-30.

