So you thought you knew what causes hardening of arteries … think again

The standard theory of heart disease states that fatty foods cause the arteries to “clog up” and narrow, which is a major feature of cardiovascular disease.  Researchers have discovered that a lack of sleep seem to have more to do with hardening of the arteries (atherosclerosis) than a fatty diet. Not getting enough sleep on a regular basis can cause a buildup of plaque in the arteries, which causes them to stiffen and eventually close.

Researchers at Massachusetts General Hospital now think that hardening of arteries has more to do with a “neuro-immune axis” linking sleep to the cardiovascular system.  Sleep helps regulate the production of inflammatory cells and maintain healthy blood vessels, and so it would follow that lack of sleep has the reverse effect.

The researchers demonstrated the effect on a group of laboratory mice.  Although the cholesteral levels of sleep deprived ice remained the same, they developed larger arterial plaques and had double the number of inflammatory cells known to contribute to hardening of arteries.

Reference

Tall AR, Jelic S. How broken sleep promotes cardiovascular disease. Nature. 2019 Feb;566(7744):329-330

Related Posts

  • How to prevent Delayed Onset Muscle Soreness?

    If your training was effective, you should feel some soreness the next day, and for two days at the most. If the second day is significantly worse than the first, and your soreness lasts into a 3rd day or beyond, you have what they call delayed-onset muscle soreness (DOMS), and it’s a sign that you trained too hard for you.  There are no hard and fast rules on what is too hard as DOMS varies from individual to individual. So now I want to talk about how to prevent Delayed Onset Muscle Soreness.

    1. Anti-Inflamatories
    As DOMS is created as a result of inflamation, in the past it was considered a good idea for those susceptible to DOMS to take anti-inflamatories e.g. ibiprofen.  However the downside of this approach is that anti-inflmatories reduce muscle growth and excessive use can damage your liver.  Hence this approach has fallen out of favour.

    2. Static Stretching

    As its not that beneficial to stretch cold muscles, start with a gentle warm up to wam up your muscles.  So both your joints and muscls are prepared and get the most benefits from stretching.

    3. Constrast Showering

    Ideally after stretching, jump in the shower and give yourself around of contrast hydrotherapy by alternating the temperature between hot and cold every two minutes. The contrast effect has definitely proven to be effective for reducing soreness and restoring muscle performance more quickly when its used the day after the workout, and any other day that a muscle is sore.

    4. Warm Up

    Ensuring that you warm up before exercising by lightly working the same muscles that you are going to train can go a long way to reducing DOMS and injuries. References Vaile JM, Gill ND, Blazevich AJ. The effect of contrast water therapy on symptoms of delayed onset muscle soreness. J Strength Cond Res. 2007 Aug;21(3):697-702.    
  • Yoga is doing what antidepression drugs can’t

    Mental health is all over the news.  Depression is one of the most common mental health conditions, and up to half of the 41 million  people taking antidepressants in [...]

  • Mundance superfoods – part 5

    My final swap is nettles for spiralina. Spirulina's deep blue-green color reveals its active ingredient — chlorophyll — clearly. Health.com explains it as one of the oldest life forms on Earth and possibly consumed in Aztec and African diets centuries ago. Today it's touted for its ability to strengthen the immune system, reduce fatigue and combat allergies. Nettles are another plant with chlorophyll that even rivals the amount found in spirulina, but they're often found in ditch banks, forests and riverbanks. It's sometimes called "stinging nettle" because it does just that; if you touch it without wearing gloves, the tiny hairs on every surface sting like a bee due to the presence of formic acid, leaving small red welts. But internally, Bon Appetit asserts, it acts like a tonic:

    "Taken over time, nettle will strengthen your circulatory, immune, and endocrine systems to promote peak function. The stronger these systems, the better position our bodies are in to deal with whatever might come our way."
    Cooked or dried, though, this pesky stinging problem goes away completely; good thing, too, because this free foraging food is highly nutritious, containing fiber, lecithin, chlorophyll, sodium, iron, phosphorus, sulfur, potassium and vitamins A and C, according to Mother Earth News. It's been used in birth rooms and battlefields to stop bleeding, both internally and externally, and is considered to purify blood, as well. As a tea:
    "It has been found to help cure mucus congestion, skin irritations, water retention and diarrhea … stimulate the digestive glands of the stomach, intestines, liver, pancreas and gall bladder. Applied externally, nettle tea … relieves rheumatism in both people and animals, makes a first-class gargle for mouth and throat infections, helps to clear up acne and eczema and promotes the healing of burns."
    To complete the series I want to point out that brocalli is arguably one of the most nutirtious vegatables readily available in supermakets.  Not only does it support normal cell function and division, it helps your body detoxify and reduces inflammation and damage from reactive oxygen species (ROS).  Another vegatable that I would highly recommend is rocket.  It has many of the same nutrients and healing compounds, including fiber, vitamins A, C (to boost the immune system) and K (for bone strength), folate, calcium, potassium, iron, magnesium, phosphorus and manganese that are found in cabbage and brocalli.  One study showed that rocket can be a powerful aid against gastrointestinal ulcers, psoriasis and skin, lung and mouth cancers. Many more vitamins and minerals help lower blood pressure and improve blood vessel function. References Bon Appétit July 19, 2017 Health December 27, 2016 Mother Earth News March/April 1981