The Impact of Sitting All Day – Part 3

In part 1, I looked at the impact of sitting on your muscles,  and in part 2 I started to explore the impact on the rest of your body.  In this post I continue to explore the impact of sitting on your circulatory system including your heart.

Heart Disease

When sitting for prolonged periods of time, muscles burn less fat and blood flows more sluggishly, allowing fatty acids to more easily clog the heart.  In 2012 Ford & Caspersen in their research paper, Sedentary behaviour and cardiovascular disease: a review of prospective studies (International Journal of Epidemiology, Vol 41, No 5 pages 1338 – 1353) showed that the people with the most sedentary time are more than twice as likely to have cardiovascular disease than those with the least.

In 2012 Zedric and Hamilton found that just a few hours sitting suppresses a gene that helps keep your cardiovascular system healthy by controlling inflammation and blood clotting.

T W Zedric & M T Hamilton, 2012 Identification of hemostatic genes expressed in human and rat leg muscles and a novel gene (LPP1/PAP2a) suppressed during prolonged physical inactivity (sitting), Lipids in Health and Disease, Vol 11 see http://www.biomedcentral.com/content/pdf/1476-511X-11-137.pdf

Cholesterol

Sitting also means that your large postural support muscles are inactive.  When active these muscles produce a quite of beneficial molecules.  One molecule skeletal muscles produce is an enzyme called lipoprotein lipase – which you can think of as a vacuum cleaner for fats in the blood stream.  A study in rats showed that after 24 hours forced inactivity, their lipoprotein lipase acitivity was reduced by 90 – 95%, which led to a 75% drip in the ability of their muscles to remove fats from their bloodstream as will as a significant decrease in “good” (HDL) cholesterol.

L Bay & Mark Hamilton, 2003, Suppression of skeletal muscle lipoprotein lipase activity during physical inactivity: a molecular reason to maintain daily low-intensity activity, Journal of Physiology, Vol 551, No 2 pages 673 – 682.See http://onlinelibrary.wiley.com/doi/10.1113/jphysiol.2003.045591/full

Related Posts

  • Why do muscles get stiff and painful?

    Muscle fibers are designed to tense and relax and go through a natural tense/relax cycle as you use your body.   A muscle under sustained tension without a corresponding relaxation phase becomes stiff and eventually spams causing pain. There are three reasons why muscles don’t relax:

    • Overuse is for example when you injury yourself in the gym.
    • Disuse is when your muscles tense when you are at your desk due to the body’s natural response to the demands and pressure you are under.  Muscles are designed to be used which means if you sit still for long periods the muscular tension doesn’t dissipate.
    • Misuse for the majority of people this is due to poor habits when walking, standing and sitting.  Sedentary lifestyles means the muscles of the legs are often held in contracted positions for long periods of time and which can lead to stiffness.  Sitting at computers for long hours keeps the neck and back in fixed positions causing the same muscles to contract which can lead to muscle tension and in some people muscle pain.
    What can I do to prevention muscular stiffness and pain?
    • Stretching Often - Stretching is, of course, a valuable way to relieve muscle stiffness.
    • Exercise - Exercise in general is extremely good for releasing muscular stiffness, improving your mood and creating good health.
    • Yoga -You can also consider yoga, which is a form of both exercise and stretching, and may have a positive effect on your future muscle discomfort.
    • General Health - Your muscles are also very sensitive to your general health as well. You need to do anything you can to make sure you're getting enough sleep, eating protein, and drinking water. These small changes are going to improve your muscle health, which should improve the way your muscles deal with demanding lifestyles.
    • Massage - Massage is an excellent way to combat muscle stiffness and pain.
    Both deep tissue and sports massage help to release muscular stiffness and pain, in addition sports massage treats sports injuries.
  • Action plan for a healthy small intestine

    The small intestine is as wide as your thumb and around 5.5m long.  It is both a food blender and assimilator as it digests more of your food than your stomach.  Food stays in the small intestine  for 1 - 4 hours before moving on to the large intestine for further processing. Maintaing a healthy small intestine is all about controlling your bacteria levels and mucus build-up on your intestinal walls which can cause havoc and deplete your energy levels.  If you have bloating, gas and loose bowel movements you may have a small intestine issues such as:

    • Candida
    • IBS
    • SIBO (small intestinal bacterial overgrowth
    Tips
    1. Cut out imflammatory drugs e.g. asprin, paracetamol and avoid alchol.
    2. Take L-glutamine and butyric acid both of these can help heal the gut, but check with a nutritionalist first as dosage is important.
    3. Drink slippery elm tea which calms inflamation of the small intestine and helps relieve IBS.
    4. Up your intake of vitamins A and D - liver is an excellent sourch of these vitamins which protect the mucus membrane of the gut.
    5. Eat more antibacterial foods such as garlic, honey and sauerkraut which preven the growth of Candida, fungus and yeast infections.
    6. Take oregano oil (Oregnano Vulgaris) which has been shown to stop Candidan in its tracks.
    7. Take probiotics daily - look for a count of 50 billion or more in each dose.
    8. Take prebiotics daily - to feed the probiotics.  Or eat food prebiotic foods such as sauerkraut or kimchi.
    9. Go gluten free.  Cut out gluten for an entire week and keep a food diary to check if your symptoms improve.
    10. Mimosa pudica an ayurvedic herb is brilliant at wiping out parasites.
    11. Eat more ant-parasitics such as garlic, thyme, chilli, tumeric and ginger.
    References https://www.bbc.co.uk/news/health-38800977 https://www.ncbi.nlm.nih.gov/pubmed/15883716  
  • Sleep is good for your arteries

    For a while there has been an assumed link between poor sleep and heart disease but it was not understood.  Now fresh evidence suggests that sleep regulates a mechanism that can help to protect arteries from hardening.  Which reinforces the notion that good quality sleep is important for cardiovascular health. Researches studied the development of atherosclerosis - the process through which plaques or fatty deposits build up inside arteries causing them to narrow and stiffen.  They discovered sleep disturbed mice:

    • Developed larger plaques in their arteries than mice that slept well.
    • Had higher amounts of circulating, inflammatory cells.
    • Produced lower amounts of hypocretin - a brain hormone that controls wakefulness.
    Researchers also saw a reduction in atherosclerosis and inflammatory cells in these mice after they recieved hyocretin supplementation. Subject to confirmation in humans, the findings demonstratet that sleep influences cardiovascular health by regulating hypocretin production in the brain. Reference https://www.nature.com/articles/d41586-019-00393-6